(2R)-1-[(5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]propan-2-ol

(2R)-1-\[(5,6-DIPHENYL\-7H-PYRROLO\[2,3-D\]PYRIMIDIN\-4-YL)AMINO\]PROPAN\-2\-OL is a synthetic small molecule belonging to the phenylpyrrole and pyrrolopyrimidine chemical classes. It is an experimental compound primarily studied as an inhibitor of serine/threonine-protein kinase Chk1 (checkpoint kinase 1), a key regulator of the DNA damage response pathway. By inhibiting Chk1 activity—which plays a central role in cell cycle arrest and DNA repair—this compound has been investigated for its potential as an anticancer agent that may sensitize tumor cells to DNA damaging agents or disrupt cancer cell proliferation. There are no approved clinical indications or marketed products containing this molecule; it remains at the preclinical/experimental stage of development.[1][2][3][4][6][8]

Other names

(2R)-1-[{5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino]propan-2-ol2-Propanol, 1-[5,6-diphenyl‑7H‑pyrrolo[2,3‑d]pyrimidin‑4‑yl)amino]- (2R)